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KMID : 0364820180540010024
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Korean Journal of Microbiology
2018 Volume.54 No. 1 p.24 ~ p.30
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Molecular epidemiological study of norovirus gastroenteritis outbreaks in Gyeonggi-Do from 2014 to 2015
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Nam Soo-Jung
Park Po-Hyun
Bang Sun-Jae
Huh Jeong-Weon
Yun Hee-Jeong
Park Kwang-Hee
Yoon Mi-Hye
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Abstract
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Norovirus infection is a leading cause of nonbacterial gastroenteritis outbreaks. New variants of GII.4 have emerged approximately every 2~3 years and have caused norovirus gastroenteritis pandemics globally. In this study, analysis and molecular genetic characteristics of the norovirus gastroenteritis outbreaks 2,917 samples in Gyeonggi-Do from 2014 to 2015. As a result, 247 samples out of 2,917 samples are positive for norovirus. Norovirus molecular genetic characteristics of the GI 8 types (GI-1, 2, 3, 4, 5, 6, 12, 14), GII 10 types (GII - 2, 3, 4, 5, 6, 11, 12, 14, 16, 17). Genome sequences of isolated noroviruses were similar to those of new GII.17 Kawasaki 2014 variants with 96.6 identity, suggesting that these viruses were imported from overseas. 44% of virus incidence was originated from school meal service. Therefore, a continuous monitoring and school sanitation should be required for preventing a massive virus outbreak.
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KEYWORD
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genotype, norovirus, outbreak, variant
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